Muscarinic regulation of cardiac L-type Ca2+ current
نویسندگان
چکیده
منابع مشابه
M1 muscarinic receptors inhibit L-type Ca2+ current and M-current by divergent signal transduction cascades.
Ion channels reside in a sea of phospholipids. During normal fluctuations in membrane potential and periods of modulation, lipids that directly associate with channel proteins influence gating by incompletely understood mechanisms. In one model, M(1)-muscarinic receptors (M(1)Rs) may inhibit both Ca(2+) (L- and N-) and K(+) (M-) currents by losing a putative interaction between channels and pho...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2000
ISSN: 0008-6363
DOI: 10.1016/s0008-6363(00)00225-x